Fybogel Mebeverine

Fybogel Mebeverine (mebeverine 135mg + ispaghula husk 3.5g) to treat constipation, pain, and bloating in IBS is available to buy online from Dr Fox.

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Buy Fybogel Mebeverine online in UK

How to order Fybogel Mebeverine online for UK delivery:

  1. Read medical information about irritable bowel syndrome
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy (tracked 24hr service)


Medication Quantity Cost
Fybogel Mebeverine (mebeverine 135mg + ispaghula husk 3.5g) 10 sachets (orange flavour) £5.20
Fybogel Mebeverine (mebeverine 135mg + ispaghula husk 3.5g) 20 sachets (orange flavour) £9.40
Fybogel Mebeverine (mebeverine 135mg + ispaghula husk 3.5g) 40 sachets (orange flavour) £18.70

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

Order value Prescription fee
up to £10 £1.00
up to £20 £2.00
up to £40 £3.00
over £40 £4.00

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail Tracked 24 Signed For (1-2 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

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About Fybogel Mebeverine

  • Fybogel Mebeverine relieves the symptoms of Irritable Bowel Syndrome (IBS) and helps restore and maintain bowel regularity.
  • Fybogel mebeverine is a sachet of orange-flavoured granules which contain 3.5g of ispaghula husk and 135mg mebeverine.
  • Take 2-3 times a day for symptoms of IBS.
  • Read the patient leaflet for a full list of side effects, cautions, and interactions with other drugs.

How does Fybogel Mebeverine work?

Ispaghula husk is a natural soluble fibre which comes from Plantago seeds. It increases the fibre and fluid within the bowel and eases the symptoms of constipation by helping gut contents to move through the bowel more easily. Ispaghula husk is also available over the counter as regular Fybogel.

Mebeverine is an anticholinergic medicine which relaxes the bowel spasm, whilst allowing the gut to continue to function. This helps relieve IBS symptoms of pain, bloating, excessive wind, and cramping. Mebeverine is also available on its own as Colofac.

Who can take Fybogel Mebeverine?

Fybogel mebeverine is especially suitable for people with IBS who suffer constipation symptoms and pain from bowel spasms, wind, and bloating.

It is important to be sure that your symptoms are caused by IBS and not something more serious. Check with your GP before using Fybogel mebeverine if any of the following apply:

  • Changed or new symptoms including a new change in bowel habit lasting over 2 weeks.
  • Over 40 years old with first symptoms.
  • New symptoms especially bloating in women.
  • New symptoms of blood in your stool or motions.
  • Feeling nauseous or vomiting or loss of appetite
  • Losing weight without dieting.
  • Pale and tired.
  • Running a high temperature (fever).
  • Travelled abroad recently.
  • Are or may be pregnant.
  • Kidney problems, urinary symptoms or take a diuretic.

Fybogel Mebeverine is not suitable for people with/who are:

  • Known or suspected allergy or sensitivity to ispaghula (more likely if you are a caregiver who regularly prepares Fybogel products).
  • Bowel blockage or bowel muscle weakness.
  • Swallowing problems.
  • Breastfeeding.
  • Unable to drink plenty of fluid (taking Fybogel without fluids can lead to bowel blockages).
  • Phenylketonuria.
  • Acute porphyria.

Fybogel Mebeverine is licensed to treat adults and children from 12 years of age, however Dr Fox can supply treatment to adults only.

Taking Fybogel Mebeverine with other medicines

Fybogel Mebeverine can be safely taken with most other medicines. Do not take other antispasmodics, e.g. Spasmonal (alverine), Buscopan (hyoscine) at the same time.

Discuss with your GP before using Fybogel Mebeverine if you are also taking any medication that causes fluid loss (diuretics) or can lead to constipation (e.g. opiate pain killers).

Discuss with your GP before using if you are a diabetic on insulin, or you take thyroid hormones as the doses may need altering.

Pregnancy and breastfeeding

In general, all medication should be avoided whilst trying for pregnancy, and when pregnant or breastfeeding.

The manufacturer advises not to use Fybogel Mebeverine if you are pregnant or breastfeeding.

Side effects of Fybogel Mebeverine

Most people experience no side effects with Fybogel Mebeverine.

It is important to drink plenty of fluids, whilst using Fybogel Mebeverine sachets, to prevent the Fybogel bulking too much and causing a bowel blockage.

A few people, especially those preparing Fybogel or Fybogel Mebeverine sachets regularly (e.g. caregivers), can become sensitized to the ispaghula through inhaling the powder. Allergy/hypersensitivity reactions can then develop. These include, itching, nettle rash/hives, nose running, watery eyes/conjunctivitis, swollen lips and face (angiooedema), difficulty breathing and rarely life threatening anaphylaxis. If any of these symptoms occur, stop using Fybogel and consult your GP or in an emergency phone the 111 or 999 service in the UK.

Further information on side effects can be found in the manufacturer's patient information leaflet.

How to take Fybogel Mebeverine

One Fybogel Mebeverine sachet should be taken twice a day (morning and evening) half an hour before meals. An extra sachet can be taken at midday if needed.

The orange-flavoured granules from the sachet should be stirred into a glass of cold water (at least 150mls) and drunk straight away. Do not inhale the powder, as this can cause serious allergy to ispaghula to develop.

Leave an hour between taking Fybogel Mebeverine and other medication.

Do not take it just before going to sleep.

Fybogel Mebeverine may take up to 24 hours to have an effect on the system. If there has been no improvement in your symptoms after 2 weeks then stop using Fybogel mebeverine and consult your GP.

Other measures to help symptoms of IBS

Diarrhoea and bloating - reduce insoluble fibre like bran, wholegrain bread, and brown rice. Reduce caffeine, alcohol, fizzy drinks, and gas-producing foods like beans and cabbage.

Constipation - try adding more soluble fibre like oats and linseed, or soluble fibre supplements like Fybogel (ispaghula). Increase the soluble fibre gradually or bloating and wind may get worse. It may take several weeks for optimal benefits.

Regular physical activity is also helpful for the bowels. Aim for 30 minutes of moderate activity at least 5 days per week.

It is also important to drink plenty of fluids (at least 8 cups per day) when constipated, especially if taking Fybogel.

Further information

Patient Information Leaflet

Illustration of patient leaflet from medicine packet

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.

Fybogel Mebeverine patient leaflet

Dr Amanda Wood

Authored 28 January 2022 by Dr Amanda Wood
MB ChB Manchester University 1984. NHS GP in Bristol. GMC no. 2855422

Reviewed by Dr C. Pugh, Dr B. Babor
Last reviewed 28 January 2022
Last updated 19 January 2024


Recent Fybogel Mebeverine reviews

Fybogel Mebeverine rated 5/5 in 1 product reviews

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Fybogel (mebeverine + ispaghula husk)

This medicine taken in combination with mebeverine and colpermin ensure regular bowel movement without bloating

Fri/03/2017 15:05
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