Spedra (avanafil) tablets to treat erectile dysfunction available to buy online in 50mg, 100mg, and 200mg strengths from Dr Fox online clinic.

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Buy Spedra online in UK

How to order Spedra online for UK delivery:

  1. Read medical information about erectile dysfunction
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy (tracked 24hr service)

Men should have an erectile dysfunction diagnosis from a GP before obtaining medication online.


Tablet type 4 tablets 8 tablets 16 tablets
Spedra 50mg £16.50 £28.00 £49.50
Spedra 100mg £19.50 £37.00 £68.00
Spedra 200mg £29.50 £54.50 £98.00

Price match guaranteePrice match guarantee
Prescription issued online - small prescription fee per order.

Compare prices: Dr Fox prices are 25%-50% lower cost than other online clinics.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

Order value Prescription fee
up to £10 £1.00
up to £20 £2.00
up to £40 £3.00
over £40 £4.00

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Prices of Spedra from UK online clinics (08 January 2023) - qualifying notes
*Dr Fox adds a small prescription fee not included in table above.
  1. The prices shown are listed by the online clinics named after a customer first enters consultation information and is offered prescriptions. It is possible these clinics may have special offers or lower prices for repeat supplies.
  2. Prices may change and are, to the best of our knowledge, accurate on the date stated. All products in stock and new condition.
  3. Dr Fox does NOT claim to provide a superior service to any of the online clinics listed. All the clinics listed, as far as we can tell, comply with all regulation and, as far as we can tell, operate to high ethical standards.
  4. Dr Fox adds a small prescription fee not included in the table (between £1 and £4 depending on value of the order).
  5. To amend the information in this table please contact us
  6. The prices listed in the table do not identify the cost of prescription medicine as online clinics charge a single fee to cover services which includes advice, consultations, prescriptions, and dispensing and supply of treatments.
  7. Where services include free delivery this is using the slowest delivery option available. Dr Fox uses Royal Mail Tracked 24.
Medication Dr Fox* Simple Online Pharmacy Lloyds Superdrug
Spedra 50mg x 4 £16.50 £19.99 £28.00 n/a
Spedra 50mg x 8 £28.00 £29.95 £46.00 n/a
Spedra 100mg x 4 £19.50 £20.95 £34.00 £32.00
Spedra 100mg x 8 £37.00 £39.50 £55.00 £53.00
Spedra 200mg x 4 £29.50 £29.95 £43.00 £41.00
Spedra 200mg x 8 £54.50 £57.95 £75.00 £72.00
UK Delivery £2.90 £3.20 included included

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail Tracked 24 Signed For (1-2 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

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About Spedra

Spedra (avanafil) was licensed in 2013 for the treatment of erectile dysfunction.

Spedra is known as a PDE5 inhibitor and works in a similar way to Viagra (sildenafil), Cialis (tadalafil), and Levitra (vardenafil), which are also PDE5 inhibitors.

How to take Spedra

Tablets should be swallowed whole. If taken on an empty stomach Spedra is likely to be most active after 15 to 30 minutes, and is likely to remain active for a period 4 or more hours.

If taken on a full stomach, absorption is likely to be delayed up to 1.5 hours or more.

As with most erectile dysfunction treatment, Spedra supports natural erections. Sexual stimulation and normal foreplay are required for treatment to work. Without it, the effects of a tablet simply wear off over a few hours.


The usual starting dose is 100mg, with subsequent doses being adjusted depending on the success of treatment. The maximum dose is 200mg a day, the minimum single dose is 50mg.

No dose reduction is required for age, although study information is not available for men over 70 years.

Spedra tablets should not be taken within 24 hours of other erectile dysfunction medication.

Spedra dosage

Spedra 50mg tablets

Spedra 50mg

Reduced dose when 100mg starting dose is highly effective.

Spedra 100mg tablets

Spedra 100mg

Starting dose recommended for most men taking for first time.

Spedra 200mg tablets

Spedra 200mg

Higher strength dose for when 100mg provides unsatisfactory results.

Consulting a doctor

All men taking treatment for erectile dysfunction should inform their GPs. Erectile dysfunction can be caused by conditions such as high blood pressure or diabetes, and these should be tested for. Men who are experiencing emotional distress, depression or relationship difficulties should see their GPs for support and advice.

Effectiveness of Spedra

Studies show approximately 50% of men taking Spedra report success, with higher doses producing better results. In the general population with ED, the mean percentage of attempts resulting in successful intercourse was approximately 47%, 58%, and 59% for the 50mg, 100mg, and 200mg avanafil groups, respectively, compared to approximately 28% for placebo.


Spedra is for men only, and should not be taken by women. Currently there is no data on sperm quality for men taking Spedra for erectile dysfunction, although no effects on sperm were found in healthy volunteers who took a single dose of Spedra. No significant effects on fertility have been found in men taking other similar medications (PDE5 inhibitors).

Side effects of Spedra

As with any medication, side effects are possible, although these rarely require cessation of treatment. The commonest side effects are headache, flushing, nasal and sinus congestion and back pain. A full list of Spedra side effects can be found in the manufacturer's patient information leaflet included in packs of Spedra tablets.

If men notice any of the following serious side effects, they need urgent medical treatment:

  • an erection that will not go away (priapism). If you get an erection that lasts more than 2 hours, this must be treated as soon as possible or lasting damage can happen to your penis (including not being able to get erections).
  • blurred vision.
  • sudden decrease or loss of vision in one or both eyes.
  • sudden decrease or loss of hearing (sometimes you may also feel dizzy or have ringing in your ears).

Cautions when taking Spedra

Coexisting medical conditions

Spedra is suitable for most men, but not all. Men who have a weak heart, recent stroke or reduced exercise tolerance should not take Spedra. Other medical conditions are listed in the manufacturer's patient information leaflet.

Checks for suitability are carried out during the online consultation at Dr Fox.

Interacting medications

Some prescription and non-prescription drugs interact with Spedra. Nitrates, used to treat angina (heart pain) and heart failure, increase the likelihood of low blood pressure. Some men use short acting inhaled nitrates, known as poppers, as a stimulant, and risk significant low blood pressure.

Other interacting medications could increase or decrease the effectiveness of Spedra. These interacting drugs are listed in the manufacturer's patient information leaflet and are checked for in online consultation.

Effects on ability to drive and use machines

Spedra has minor influence on the ability to drive and use machines. As dizziness and altered vision were reported in clinical trials with avanafil, patients should be aware of how they react to Spedra before driving or using machines.

Patient Information Leaflet

Illustration of patient leaflet from medicine packet

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.

Spedra Patient Information Leaflet

Alternative treatment

Cialis (tadalafil), Viagra (sildenafil), and Levitra (vardenafil) are alternative tablet treatments for erectile dysfunction and are also available to buy in various strengths and pack sizes after completing the same medical consultation.

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Dr Tony Steele

Authored 16 May 2014 by Dr Tony Steele
MB ChB Sheffield University 1983. Former hospital doctor and GP. GMC no. 2825328

Reviewed by Dr C. Pugh, Dr B. Babor, Dr A. Wood
Last reviewed 18 August 2021
Last updated 19 January 2024


Recent Spedra reviews

Spedra rated 3.15/5 in 176 product reviews

See over 40,000 service reviews of Dr Fox

Spedra 50mg

Did not work

Tue/01/2024 21:35
Anonymous Verified

Spedra 100mg

Good effect with minimal side effects like headache or nasal congestion

Wed/12/2023 11:51
Anonymous Verified

Spedra 100mg

Ok not brilliant

Mon/10/2023 11:42
S. Thompson Verified

Spedra 200mg

Not very good

Mon/10/2023 11:41
S. Thompson Verified

Spedra 100mg

Didn't work well for me.

Wed/10/2023 15:12
Anonymous Verified

Read more reviews

The order process

Choose medication, register, and pay

Dr Fox issues prescription online

Pharmacy team post medication direct